“Synthesized” or “Synthesised”—What's the difference?

Usage by country

Where each spelling is used

Of the 12 countries below, 7 prefer “synthesized” and 2 prefer “synthesised”. Usage levels are out of 100; the more common spelling in each country is in bold.

Usage level out of 100 (if available).
Country	synthesized	synthesised	Preference
United States	99	1	“synthesized”
United Kingdom	45	55	“synthesised”
India	69	31	“synthesized”
Philippines	99	1	“synthesized”
Canada	96	4	“synthesized”
Australia	47	53	“synthesised”
Liberia	0	0	Not enough data
Ireland	56	44	“synthesized”
New Zealand	50	50	No clear preference
Jamaica	100	0	“synthesized”
Trinidad & Tobago	100	0	“synthesized”
Guyana	0	0	Not enough data

Usage

Examples in context

Real sentences for each spelling. Hover an example to copy it.

“synthesized”

Cyanogen iodide was first synthesized in 1824 by the French…
…of related chemical compounds are synthesized by humans.
These two approaches could be synthesized in the investigating cultural systems.
Seed continued the research and synthesized several more molecules using Dr.…
…a few compounds have been synthesized, they are not fully studied;…
Acetylcholine is synthesized from choline and a donated…
Ethylene thioureais synthesized by treating ethylenediamine with carbon
…still not settled – Piutti synthesized asparagine and thus determined its…
…as well as 15 others synthesized from amino acids, (di-, tri-,…
HMB is synthesized in the human body through…

“synthesised”

However, isoprenoidal GDGTs can be synthesised in the terrestrial environment and…
…and is frequently discordant, featuring synthesised sounds reminiscent of passing heavy…
These substances are synthesised during autumn and their concentration…
…aromatase but estrogen that is synthesised in breast tissue and around…
…arsine compound which was already synthesised in 1854.)
…a separate dictionary; the speech synthesised by the engine claims clear…
…more stable compound artemether was synthesised from artemisinin.
They are synthesised with a 19- to 28-residue…
…sent to Zimmer to be synthesised.
…international-exercise which catalogued, analysed, and synthesised: written submissions and expert testimony…

Examples are Wikipedia snippets under the CC ShareAlike 3.0 license.

Too much to remember?

Looking for a tool that handles this for you wherever you write?

Install Sapling Try the grammar checker